Accuracy of non-invasive assessment of pulmonary pressures by Doppler echocardiography versus right heart catheterisation

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Pulmonary hypertension (PH) is haemodynamically defined according to the latest ESC/ERS guidelines as a mean pulmonary arterial pressure (mPAP) > 20 mmHg at rest. Transthoracic echocardiography (TTE) non-invasive and widely available initial screening test for PH, though studies correlation between echo-derived estimates systolic artery (sPAP) right heart catheterization (RHC) measurements have provided mixed results few used mPAP utilising regurgitation (PR), especially since recent redefinition PH. Aim 1) To investigate TTE-derived sPAP RHC in large contemporary cohort patients, using new PH definition 2) assess impact potential confounding factors, such rhythm, quality continuous wave Doppler envelopes, chronologic proximity TTE severity tricuspid valve (TR PR). Method A single centre database newly diagnosed patients by January 2010 December 2020 was retrospectively reviewed analysed. Patients who had medication changes were excluded. Investigators analysed individual TR PR tracings off-line all eligible patients. Spearman (r) explore parameters. Results Overall, 503 during study period (Table 1). All TTEs performed within 5-month interval from RHC. Median age 63.2 (16.0 – 91.1) years. There moderate-strong TTE-assessed atrial ( r=0.47, p < 0.001), r=0.45, <0.001) r=0.61, <0.001), with an improved when factors (rhythm, envelope, severity) considered re-analysed r=0.63, <0.001 sPAP, r=0.58, p< 0.001 mPAP, Table 2). When only 24 hours assessed, significantly (r = 0.71, however this could not be assessed due insufficient number Conclusion These findings are agreement previously published data, suggesting that there least moderate PAP RHC, which stronger time two investigation short. While gold standard diagnosing assessing remains very useful tool, but if standardised meticulous, order improve accuracy.